Jumping realities:

Nick is a shorter than average chubby man with fair skin, green eyes and shoulder-length, blonde hair.

He is currently wearing elegant clothing.

Nick found a way to jump to another realities and jump to another world but once the portal close Nick realize he was now stuck in this dimension. In this world there has been a recent outbreak of a new virus that swaps the genders of people. Nick found out the hard way while he tried to open the portal again he slowly transform into a woman.

There seems to be no cure in sight, so she might be stuck like this permanently and stuck in this reality.

Turning my dad into a Were-kid by accident:

Julie is a very tall sleek teen with brown skin, gray eyes and elbow-length, thick, bleached hair.

She is currently wearing hipster clothing.

She was mad at her father after they got into a fight and since Julie's mom side of the family has connections to magic but only the female side. So Julie took out her grandmothers spell book and started to cast a spell when she sneeze and screw up the spell. After a bolt of energy struck her dad he began to change and age down to a little girl.

The changes are temporary and he'll change back at night, he'll transform again every day. So now Julie will have to babysit her dad/sister.

Went to bed as a pre-teen woke up as a mom:

Jackie is a ridiculously short pre-teen with pale skin, pink eyes and shoulder-length, blonde hair.

she currently wearing sleep clothing.

Jackie was dreaming about her future and slowly but surely transform into a mom, when she woke up she realize it was no dream.

The changes are permanent! There's no way for Jackie to return to normal her normal age! But at least she doesn't have to go to school but no has to raise 3 kids.

Mike is a very short hairy man with tan skin, green eyes and short, thick, red hair.

He is currently wearing camping clothing.

Mike very slowly transform into a giant hippogriff after eating some berries that he found in the woods.

The changes are temporary and he'll return to normal in a month, but if he ate the berries again the duration increases by eleven years!

The Wrong meds:

Henry is a average sized pudgy man with lightly tanned skin, gray eyes and short, thick, black hair.

He is currently wearing vintage clothing.

Henry purchase some pills over the Dark web  and consume one of them. After a couple of moments his body transforms into that of a snail.

He check the instructions as he was curious about how long transformation lasts, it reads: "Take one for temporary effects, take two for permanency". Henry is now a snail for the rest of his life.

Waking up in my normal body:

Chris is a very tall buff man with pale skin, red eyes and short, wooly, dirty blond hair.

He is currently wearing almost no clothing.

Chris wonder how life would've been if he was born as a girl, suddenly the world starts warping as he transform into a busty female.

The changes are permanent.

Christine is totally unaware of her transformation.

Kidnap by a crazy doctor:

Amanda is a taller than average broad woman with amber skin, blue eyes and shoulder-length, swept-back, dark brown hair.

She is currently wearing punk clothing.

Amanda was instantly transform into a pregnant soccer-mom after being kidnapped by a mad doctor and used for their experiments.

The changes are temporary and she'll return to normal in a few years, but if she spend money the duration increases by three years!

Got turn into a Fuck plant at a costume party:

Jenny is a very short very endowed woman with fair skin, gray eyes and very long, thick, black hair.

She is currently wearing Pokémon girl  Costume.

After getting hungry Jenny ate some weird fruit in her friends fridge and instantly transform into a fuckplant.

The changes are temporary and she'll change back in the morning, she'll transform again every full moon!